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This study involved 481 dogs with cancer and found that long nosed dogs, like greyhounds and collies, were twice as likely to get nasal cancer if they lived with smokers
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Under conditions of cellular homeostasis, the stability and function of p53 protein are controlled by MDM2 that targets p53 for degradation and directly inhibits p53 activity by binding to the transcriptional activation domain 17
But public health experts have expressed shock at the policy reversal, saying it could cost up to 5,000 lives a year, and be particularly detrimental to Mori, who have higher smoking rates
